Computational solutions supporting research development
Computational systems designed to meaningfully support research and development processes - from complex data analysis to molecular and materials modeling.
Built to improve efficiency, decision quality, and development pace in biotech and pharmaceutical environments.
Omics Microbial Genome Similarity Search with FASTQ (MGSS-FASTQ)
Develop a tool to enable rapid identification of microorganism genomes from raw sequencing data generated by NGS/MPS and stored in FASTQ files, leveraging the RefSeqMasher algor...
Chemistry De novo Design and Synthesis of Selective Inhibitors for Carbonic Anhydrase Isoforms II, IX and XII
Establish a de novo, structure-based workflow to design and synthesize small-molecule inhibitors selective for carbonic anhydrase isoforms II, IX, and XII, achieving nanomolar b...
Chemistry De novo Design of Dual mTOR/EGFR Inhibitor for a Double-Punch Effect
Develop a single small molecule capable of selectively inhibiting both mTOR (serine-threonine kinase) and EGFR (tyrosine kinase) by identifying a shared structural motif that en...
Chemistry Hybrid Chemical–Bioconjugation Polypeptide Synthesis (Semaglutide)
Validate a streamlined hybrid route to produce semaglutide suitable for pilot‐scale manufacturing, using microwave‐assisted SPPS and site‐selective bioconjugation.
Chemistry Multifunctional Agents Targeting Microtubules
A concise in silico workflow was used to design, synthesize, and validate small molecules that disrupt microtubule dynamics, induce G2/M cell cycle arrest, and demonstrate enhan...